Penegra is a generic medication containing the active ingredient sildenafil citrate, prescribed for the treatment of erectile dysfunction (ED). It functions as a phosphodiesterase type 5 (PDE5) inhibitor, which works by augmenting the natural erectile process that occurs with sexual stimulation. The medication does not induce an automatic erection; rather, it enhances blood flow to the penis when a man is sexually aroused. Penegra is typically taken orally approximately 30 to 60 minutes before anticipated sexual activity, with its therapeutic effects lasting for 4 to 6 hours. Common side effects are generally mild and can include headache, facial flushing, indigestion, and nasal congestion. It is critically important to note that Penegra is absolutely contraindicated for use with nitrate medications due to the risk of a severe and potentially fatal drop in blood pressure. A comprehensive medical evaluation is essential to determine its suitability and ensure safe use for any individual.