Joined Jul 2025 New York, USA
Zenegra is a generic medication containing Sildenafil Citrate, prescribed for the treatment of erectile dysfunction (ED). It belongs to the PDE5 inhibitor class of drugs, working by enhancing the natural erectile process. Upon sexual stimulation, nitric oxide is released, leading to increased levels of cGMP, which relaxes the smooth muscles of the corpus cavernosum and increases penile blood flow. Zenegra's role is to inhibit the PDE5 enzyme that degrades cGMP, thereby sustaining the erection. The medication requires sexual arousal to be effective and is typically taken 30-60 minutes before intercourse, with a duration of action of 4-6 hours. Common side effects, stemming from its vasodilatory properties, include headache, flushing, and nasal congestion. Critically, Zenegra is absolutely contraindicated with nitrate medications, as the combination can cause a severe and life-threatening hypotensive state. A full medical evaluation is essential to ensure patient safety.
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